PDE5 inhibitor protects testes
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چکیده
منابع مشابه
Green Tea Protects Testes against Atrazine-induced Toxicity in Rat
Background: Atrazine (ATZ) is a common herbicide in agriculture for control of grass and broad-leaved weeds. It persists in the environment and causes reproductive problems in both human and animals. The present study was aimed at protective effect of green tea against ATZ toxicity in the reproductive system of male rats. Methods: The present study was performed in Veterinary School, Shahid ...
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Smoking is associated with endothelial dysfunction. The purpose of this study was to determine the effect of sildenafil, an inhibitor of phosphodiesterase type 5 (PDE5), on endothelial function in smokers. We evaluated the forearm blood flow (FBF) responses to acetylcholine (ACh), an endothelium-dependent vasodilator, and to sodium nitroprusside (SNP), an endothelium-independent vasodilator, be...
متن کاملPDE5 inhibitor efficacy is estrogen dependent in female heart disease.
Inhibition of cGMP-specific phosphodiesterase 5 (PDE5) ameliorates pathological cardiac remodeling and has been gaining attention as a potential therapy for heart failure. Despite promising results in males, the efficacy of the PDE5 inhibitor sildenafil in female cardiac pathologies has not been determined and might be affected by estrogen levels, given the hormone's involvement in cGMP synthes...
متن کاملgreen tea protects testes against atrazine-induced toxicity in rat
background: atrazine (atz) is a common herbicide in agriculture for control of grass and broad-leaved weeds. it persists in the environment and causes reproductive problems in both human and animals. the present study was aimed at protective effect of green tea against atz toxicity in the reproductive system of male rats. methods: the present study was performed in veterinary school, shahid bah...
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The objective of this study was to evaluate the effect of short-term levosimendan exposure on oxidant/antioxidant status and trace element levels in the testes of rats under physiological conditions. Twenty male Wistar albino rats were randomly divided into two groups of 10 animals each. Group 1 was not exposed to levosimendan and served as control. Levosimendan (12 µg/kg) diluted in 10 mL 0.9%...
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2012
ISSN: 1759-4812,1759-4820
DOI: 10.1038/nrurol.2012.170